Mapping the architecture of the initiating phosphoglycosyl transferase from S. enterica O-antigen biosynthesis in a liponanoparticle

Bacterial cell surface glycoconjugates are critical for cell survival and for interactions between bacteria and their hosts.Consequently, the pathways responsible for their biosynthesis have untapped potential as therapeutic targets.The localization of many glycoconjugate biosynthesis enzymes to the membrane represents a significant challenge saint

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Molecular pathways identified from single nucleotide polymorphisms demonstrate mechanistic differences in systemic lupus erythematosus patients of Asian and European ancestry

Abstract Systemic lupus erythematosus (SLE) is a multi-organ autoimmune disorder with a prominent genetic component.Individuals of Asian-Ancestry (AsA) disproportionately experience more severe SLE compared to individuals of European-Ancestry (EA), including increased renal blue square tablecloth involvement and tissue damage.However, the mechanism

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Transportation of patines from the offices

Introduction: City Institute for Emergency Medicine Belgrade provides 24 hours a day health care for citizens, both in the fieldwork and inside its offices of the Central building.Critical patients that cannot be treated completely in these facilities and patients that require further diagnostic procedures and observation are being transferred to t

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